11 Top DISEASE ASSOCIATED with IMMUNE SYSTEM Questions and Answers pdf

1. The HIV virus infects primarily

A. brain cells
B. cells in the immune system
C. red blood cells
D. liver cells

Answer: B

2. Chronic granulomatous disease results from a failure to perform oxidative burst. This deficiency would be most likely to interfere with

A. CTL killing of viruses
B. dendritic cell activation to become a mature APC
C. infected cell processing of virus peptides
D. macrophage intracellular killing of bacteria

Answer: D

3. Difficulties with somatic gene therapy arise from all of the following except

A. GVHD caused by mature T cells in the transplanted cells
B. inserting a gene so that it will function properly
C. limited life span of more mature hematopoietic cells
D. transducing genetic material into stem cells

Answer: A

4. A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind

A. Leu or Ileu
B. His or Pro
C. Tyr or Phe
D. Ser or Thr

Answer: C

5. Retinoblastoma is due to a mutation in a

A. kinase
B. tumor supressor
C. cyclin
D. viral gene

Answer: B

6. An autoimmune disease is

A. AIDS
B. Measles
C. Lupus
D. Mumps

Answer: C

7. If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced

A. alternative complement activation.
B. CD8 T cell-mediated cytotoxicity
C. macrophage activation to vesicular pathogens
D. IgG synthesis

Answer: A

8. Specific translocations are associated with

A. colon cancer
B. breast cancer
C. pancreatic cancer
D. some leukemias

Answer: D

9. To treat HIV infections using drugs, the major problem is that

A. the drugs that are good inhibitors cannot by synthesized
B. the drugs interfere with normal digestion
C. the virus particles with altered (mutant) proteases arise
D. the drugs are rapidly degraded

Answer: C

10. The primary reason for AIDS, a deadly disease is that it

A. is caused by a virus
B. is caused by a bacterium
C. destroys key components of the body’s internal defense system
D. causes a breakdown of the body’s inflammatory response

Answer: C

DISEASE ASSOCIATED with IMMUNE SYSTEM Questions and Answers ::

11. A selective IgA deficiency would be expected to result in problems with

A. bacterial infections
B. infections following dental work due to bacteria entering the bloodstream
C. mucosal pathogens
D. pathogens which can survive inside macrophages

Answer: C